Vaccine exemption information for each state is provided below thanks to the National Vaccine Information Center. Parents, I want you to be informed and know your rights for your children’s health, protection and welfare. You can access your state’s vaccine policies and laws by locating your state in the text links below. (source)
As home-educators, we used the religious exemption for vaccinating our children, and (when asked) it never became an issue when I mentioned we had a lawful state exemption.
We were also members of and backed up by the Home School Legal Defense Association (HSLDA) which I highly recommend.