[These excerpts on DMSO for chronic lung diseases are brought to you by The Midwestern Doctor. He opens the door to the amazing healing properties of DMSO for COPD and so much more. I have shared just portions from his VERY long article to make it more readable, so look for the different topical sections that are of importance to you – including sections on where to get it and how to use it at the end. ~Jacqueline]
Story at a Glance:
•Chronic respiratory diseases, while quite profitable, remain an area that medicine struggles with, and as such many with them are subjected to a life of healthcare expenses, impaired stamina, and in many cases, a painful decline until they succumb to the illness.
•DMSO is an “umbrella remedy” capable of treating a wide range of challenging ailments due to its combination of therapeutic properties (e.g., reducing inflammation, improving circulation, restoring damaged organs, and reviving dying cells).
•DMSO is also quite useful for addressing the infections that frequently accompany these disorders, as it has antimicrobial activity, reduces damaging lung inflammation, and potentiates many natural antimicrobial therapies by combining DMSO with a natural antimicrobial.
•A large volume of published data and many user reports show that DMSO often produces remarkable results for a wide range of respiratory disorders, of which asthma, chronic obstructive pulmonary disease and pulmonary fibrosis, and pneumonia will be covered here.
• We will also examine the most common protocols used for them and other natural approaches that also aid in their treatment and guidelines for general DMSO procurement and use.
Since childhood, I have known numerous smokers who had slow agonizing deaths from COPD (chronic obstructive pulmonary disease), which were often quite traumatic for their family and friends, particularly as they became increasingly disabled from their loss of respiratory function.
Once I entered medicine, I lost count of how many COPD patients were subjected to the same medical protocols (which they often could not refuse as people will do anything to be able to not suffocate), and then be hospitalized again for pneumonia (a common COPD complication) making them unable to breathe, and before long enter a cycle of ever more frequent repeat hospitalizations until they die.
Note: steroids are frequently used to manage COPD and slow the destruction of the lungs. Yet, steroids have a variety of side-effects, including suppressing the immune system, which along with the reduced ability to clear bacteria from the airway seen in COPD, makes patients much more vulnerable to pneumonia.
When I later learned that the lungs concentrate a coating of glutathione (at levels 100 times than in other parts of the body) to protect them from damage, and that restoring this coating with nebulized glutathione could (without side-effects) prevent further progression of COPD, I was overjoyed (e.g., see this study and this study or the even more dramatic results when used for a COPD exacerbation).
Unfortunately, this idea never caught on, and most of my conventional colleagues were not open to it (although many integrative doctors and naturopaths offer it for both COPD and chronic damage from wildfire and smoke inhalation). Here’s how to very easily nebulize glutathione for smoke.
This is to be expected, as, like many businesses, medicine revolves around recurring sales, and COPD is one of its core markets (as COPD patients are on medications for life and often need more of them as the disease progresses). This in turn, helps to explain why chronic diseases of the respiratory tract are the fourth most common cause of death in the United States, and in the United States alone, 24 billion dollars was spent on COPD in 2023. In short, this is not a market that the medical industry will ever willingly relinquish, regardless of the suffering that is created.
DMSO, the Perfect Umbrella Remedy
In medicine, there are a few therapies that have the ability to cure a wide range of diseases, and as such are referred to as “umbrella therapies.” Dimethyl sulfoxide (DMSO) is a forgotten natural therapy which rapidly treats a wide range of conditions and that many studies have shown is very safe.
DMSO, as such, has repeatedly been shown to be remarkably effective for a wide range of disorders including:
Strokes, paralysis, a wide range of neurological disorders (incl. Down Syndrome and dementia), discussed here.
A wide range of tissue injuries, such as sprains, concussions, burns, surgical incisions, and spinal cord injuries.
Chronic pain (e.g., from a bad disc, bursitis, arthritis, or complex regional pain syndrome), discussed here.
A wide range of autoimmune, protein, and contractile disorders, such as scleroderma, amyloidosis, and interstitial cystitis (discussed here).
A variety of head conditions, such as tinnitus, vision loss, dental problems, and sinusitis (discussed here).
A wide range of internal organ diseases, such as pancreatitis, infertility, liver cirrhosis, and endometriosis (discussed here).
A wide range of skin conditions, such as burns, varicose veins, acne, hair loss, ulcers, skin cancer, and many autoimmune skin diseases (discussed here).
Many challenging infectious conditions, including chronic bacterial infections, herpes, and shingles (discussed here).
Many aspects of cancer (e.g., many of cancer’s debilitating symptoms, making cancer treatments more potent, greatly reducing the toxicity of conventional therapies, and turning cancer cells back into normal cells), discussed here.
Additionally, DMSO possesses a unique ability to enhance the absorption of medications and natural therapies by facilitating their passage into the body.
This property has transformed the way conventional and natural medicine is practiced, opening up nearly limitless possibilities for incredible therapeutic combinations, and most importantly, DMSO is extremely safe (provided it’s used correctly).
While unbelievable, consider for a moment this 1980 report by 60 Minutes that corroborates much of that:
15 minutes.
DMSO, Nature’s Healer
Discovered by Alexander Zaytsev in 1866, DMSO, or dimethyl sulfoxide, is a compound that is found in tree sap. In trees, DMSO functions as a solvent, facilitating the transport of nutrients and other compounds throughout the plant. It helps in the movement of substances through the xylem and phloem, which are the main conduits for fluid transport within a tree. This ability to cross membranes easily makes it valuable for trees, as well as for animals and humans. (Other tree sap products are maple syrup, birch syrup, latex, rubber, pine resin, and amber.) (source)
FDA Went To War with DMSO, Then Was Forced to Relent
Since DMSO was widely available in the 1960s, it quickly spread like wildfire across America (particularly due to how rapidly it alleviated “incurable” pain). Regrettably, the FDA then stepped in and went to war with DMSO to protect their status quo. In the decades that followed, despite the public, the scientific community, and Congress petitioning the FDA to rescind their prohibition on DMSO, it’s all fallen on deaf ears.
This continued until the 1994 DSHEA act (passed in response to the public outrage over the FDA raiding supplement providers at gunpoint) simply took away the FDA’s ability to regulate natural medicines that DMSO was able to re-enter the marketplace. Still, sadly by this time, despite thousands of studies supporting its use, and it being widely used outside the United States, DMSO had become another forgotten side of medicine.
Thousands of DMSO Testimonials
I’ve received numerous testimonials from readers around the world about the life-changing effects DMSO has had on them. Recognizing the importance of not letting these stories become forgotten, I’ve devoted a significant amount of time to compiling them all here. While I know I’ve missed a lot (since they appear in so many places), there are now over 3,000 of them.
In those testimonials, numerous people shared that DMSO had either improved or reversed their COPD (or pulmonary fibrosis). These chronic, debilitating lung conditions are very difficult to treat within the standard medical paradigm. One reader, Rebecca Cunningham, shared that DMSO had saved her beloved neighbor from COPD (“I am LITERALLY watching a miracle happen”).
I have received many similar stories (most of which can also be viewed online where they were posted). To make this as concise as possible, I condensed these details to their essentials. One of the things I find noteworthy about these is how often they had not intended to cure their lung issue, but rather it happened incidentally while using DSMO for something like pain.
I was also told I had emphysema in the upper part of my lungs. I had 2 strokes due to a clogged left carotid. I had purchased DMSO to apply on my scar the scar diminished pretty quickly. I also rub it on my chest. Then I purchased a nebulizer, added 70/30 DMOO. Did the treatment everyday for a 1 week, now on maintenance a twice a weekly. This is how I cured my COPD. I also apply a drop to my ear to lessen the noise from tinnitus, it didn’t get rid of it completely, but the noise went from 35 decibels to five, I can live with this. I also take it twice a week orally to deal with stomach issues which I alternate with CD.
Thank you for posting this. I have severe COPD. I’ve been using DMSO for about 2 weeks now and it’s a big change for me. So Thanks again.
Thank you for your efforts on Jenny’s behalf. She is now about ten days into Dan’s —[COPD DMSO nebulization] process. She has seen positive effect, especially the loss of panic/despair.
Is it possible that continual application of DMSO cream to my husbands bad back could be helping his lungs? He seems to have more energy, is doing more, and I’m wondering! I cover his whole back, shoulders and side ribs down to the bottom each morning. It’s amazing…he’s 85, with pulmonary fibrosis and emphysema and he’s getting stronger, refused his wheelchair to go to church yesterday, makes the coffee for me before going to bed, and ONLY DMSO back rub and sunlight are different. This was unexpected, and the docs around here don’t seem to have ever heard of DMSO!!! Thanks so much. I don’t want to lose him!
I am using DMSO via a nebulizer, (as well as topically) and it seems to be showing significant improvement in my lungs! I was on 4 liters and now use NO supplemental Oxygen or any other medicine for my lungs, (I was also taking Trelogy). Despite decades of excessive smoking and drinking) and I am seeing remarkable results.
DMSO helps my husband’s lungs when I rub his back and rib cage…. And helps with his chronic pain from failed back surgery! We are old, but we don’t take or need NSAIDS anymore! It’s a miracle!
We started DMSO gradually to make sure there were no bad effects [for COPD]. First topical 50/50 DMSO & aloe Vera on his chest for a week, then a 50/50 mix with distilled water in his nebulizer 1x a day. after 3 days, he was so blown away by the positive results…he is in his late 70’s.
I found out about DMSO about a week ago and did the research and started using it 50/50 DMSO/Distilled water. I have COPD. DMSO has helped tremendously. I’m blown away and ecstatically happier. We have a major wild fire right now too and I can breathe! I mean DEEP breaths.
I had a patient with scleroderma and interstitial lung disease (which had put them on the transplant list) but after receiving DMSO, the lung recovered and they no longer need a transplant. I also just saw a patient with sarcoidosis treating himself with dmso nebulized. He said it made a big difference—James Miller MD
Pulmonary DMSO Data
A few months ago, while researching DMSO combination therapies, I realized the German DMSO community had done the most work in this area (particularly in regards to natural therapies) and began extensively studying their work. In parallel, about a month ago, I realized there was a way to access and summarize thousands of DMSO studies from Russia, China, Germany, and South America, so most of my focus recently has gone into trying to compile it. From that, I discovered that there is a lot more data supporting the use of DMSO in a wide range of lung conditions than I had originally anticipated.
Lung Injury
DMSO’s ability to rescue damaged cells from death, stabilize cell membranes, reduce harmful inflammatory processes (which often set in after injuries or loss of blood), and restore the microcirculation have allowed it to be invaluable for a myriad of diseases within the internal organs (e.g., pancreatitis, liver cirrhosis, or infarctions to any organ).
As such, DMSO also protects the lungs from devastating injuries.
Supporting studies include:
• DMSO was found to prevent significant inflammation and tissue injury, which follows a significant traumatic impact on the lungs.
• DMSO prevented injuries from respiratory anoxia (being unable to breathe air in).
• DMSO was found to prevent lung injury from hemorrhagic shock (significant blood loss) and transfusing lost fluids back into the circulation.
• In mice exposed to lethal radiation doses, oral DMSO prior to radiation allowed all to survive, and protected many parts of the body including the lungs. (Note:If you cannot access the following cnki.net studies, it often requires using a VPN until you find an acceptable IP, as these databases are to some extent, restricted to their region.)
• Following cold stress from freezing temps, DMSO reduced lipid peroxidation and stress-induced injuries in the stomach and lungs.1,2,3
• In rats with lung injury caused by blood flow loss, treatment with 5% DMSO reduced lung swelling, lowered harmful inflammation markers, and decreased mitochondrial DNA release, helping protect lung tissue by calming the body’s inflammatory response. Separately, DMSO (5% at 5 ml/kg) given two hours before the injury, reduced lung tissue swelling and damage, [lowered the wet-to-dry weight ratio] inflammation, and inflammatory markers (IL-6, IL-8, TNF-α), while lowering harmful mitochondrial DNA expression1,2
Note: another study also found DMSO prevented lung ischemia-reperfusion injuries.
Note: I have also seen a few reports of people improving pulmonary emboli with DMSO, such as by applying to the site of a known clot (which if you decide to do so, must be done in conjunction with conventional care as PE’s are life-threatening).
COPD and Pulmonary Fibrosis
DMSO has been repeatedly shown to improve lung fibrosis:
• DMSO at 0.5-3%, in a dose dependent fashion, roughly halved the proliferation of fibroblast cells, suggesting it could reduce the fibrosis seen in chronic lung diseases.
• In 82 Wistar rats, DMSO (2 ml/kg) reduced pulmonary fibrosis, normalizing lung white blood cell counts.
• DMSO reduced chronic pulmonary fibrosis, particularly when combined with zinc.
Likewise, DMSO addresses the inability to bring oxygen into the body:
• DMSO was found to prevent oxygen deprivation and inability to exchange gasses through the lungs, which results from an Ehrlichia ruminantium infection (which is typically fatal).
• For older patients with chronic respiratory insufficiency (leading to chronically low blood oxygen levels, elevated carbon dioxide levels, and an abnormal acid base balance) due to issues in the lungs or bronchi, daily intramuscular DMSO was found to bring about a recovery without the need for hospitalization in 81%.
Other studies have also shown that DMSO helps with chronic non-specific lung diseases.
Toxic Environmental (incl. Smoke) or Work Exposures
Chronic lung issues come from either severe respiratory exposure to a toxin or numerous small ones. I know numerous people who developed chronic lung issues after exposure to wildfire smoke. Extensive research from Hawaii has shown the majority of those in the Lahaina fire two years later still have symptoms (e.g., headaches, dizziness, weakness, breathing issues, sore throats, eye irritation, chest pain or tightness, nausea, vomiting, anxiety and suicidal thoughts).1,2
There is significant evidence particulate matter exposure (e.g., from car exhaust, air pollution, or cigarettes) damages the blood vessels and is well known to increase cardiovascular disease and death.1,2,3 Coal miners with a high coal particulate exposure for example, are more than twice as likely to die from heart disease, and coal dust inhalation has been found to cause atherosclerosis. Likewise, dense wildfire smoke exposure has been shown to increase ER visits amongst older adults by 42% for heart attacks and 22% for ischemic heart disease.
DMSO has been shown to significantly reduce the damage caused by airway toxins:
• Giving DMSO before (a toxin) was found to prevent the inflammation, cellular damage, and edema caused in the lungs.
• In human lung cells exposed to harmful cigarette smoke, a mixture of tea polyphenols and DMSO provided strong protection by significantly reducing DNA damage, chromosome abnormalities, and gene mutations, showing that DMSO combined with antioxidants can help shield cells from smoke-related genetic harm.
Since smoking is quite challenging to quit, this implies DMSO could be taken to counteract the harmful effects of that habit, however, I do not believe this is wise. As one study that combined DMSO soluble particles with cigarette smoke found, low doses protected the vascular smooth muscles, but higher doses (which would likely be exceeded with chronic smoking) increased the harm and cell death in the blood vessels. As such, I believe if someone with COPD plans to implement a DMSO nebulization protocol, they must first be done with smoking.
Cystic Fibrosis
There is some data suggesting DMSO can improve the abnormal proteins which characterize cystic fibrosis, dissolve excessive mucus, and provide helpful antibacterial effects. Currently, I only know of one case where it was used for the condition which was recently shared with me by a colleague.
I am currently treating a 45 year old CF patient with DMSO and glutathione. She was in the beginning stages of getting worked up for lung transplant. We’ll have PFT’s from before treatment and updates every 3 months starting in August. One month in, she’s feeling like a teenager again, exercising and has been illness free for 4 weeks now, which is the longest period without antibiotics since she was in her 20’s. She tells me I can share all the details of her case if you’d find them useful.
Respiratory Infections Including Tuberculosis
My English bulldog had a very stubborn case of pneumonia. She was on three different antibiotics over an eight week period & nothing seemed to help. Then we added DMSO to the treatment protocol! 1 week later her lungs were clear.
As that shows, DMSO is often immensely beneficial for many different infections, particularly when combined with other antimicrobial agents, as DMSO both enhances their ability to penetrate into (and throughout) the body and, by penetrating microbes, remove their antimicrobial resistance. A lot of research (and many readers) has shown DMSO can frequently treat chronic infections or life threatening infections that do not respond to standard treatments. In many cases, simply being combined with a natural antimicrobial is effective, rather than a potentially toxic pharmaceutical drug.
Tuberculosis is the most deadly infection in the world, particularly due to its ever increasing antibiotic resistance. Many lab studies (summarize here) have shown DMSO directly inhibits the bacteria’s growth and increases its sensitivity to the antibiotics used to treat the infection by 3 to 200 times,1,2,3,4 including in bacterial extracts from tuberculosis patients.1,2 Likewise, in guinea pigs with isoniazid resistant tuberculosis, all died despite isoniazid treatment, whereas if DMSO was given prior to it, they all survived.
DMSO dramatically improves outcomes in patients with destructive pulmonary tuberculosis who received nebulized antibiotics mixed in DMSO. Also in children who contracted tuberculosis from contaminated vaccines.
Many have reported successfully curing chronic lung infections (or coughs or sinusitis) with nebulized DMSO (…see more below on how).
Acute Respiratory Distress Syndrome (ARDS)
ARDS, a life-threatening condition where the alveoli fill with fluid and then collapse (which typically follows severe pneumonia), is quite challenging to treat (and a common reason people end up on ventilators). Fortunately, many studies have shown DMSO helps the condition:
•In hamsters with ARDS, DMSO reduced the inflammation and fluid in the lungs significantly. Identical results were found in a mouse study, while another found DMSO kept all treated mice from dying (58% of controls died), and maintained the ability of the lungs to produce ATP.
In one human study, DMSO was used for ARDS to produce a dramatic improvement in all three patients who received it (e.g., one patient’s lungs were completely normal after a week) and prior to receiving DMSO all three were near death. Additionally, in the one case when DMSO was nebulized, the improvement occurred in 1 hour.
Asthma
Many readers with asthma have shared DMSO changed their life:
Holy moly, this is crazy. Dosed this weekend, 3 days, taking a short break (just can’t have that odor during office hours), and already my asthma is almost non-existent. Beyond belief.
I’ve been using DMSO for about a week now for a rather persistent asthma [and sudden heart palpitations]…and have felt a marked improvement to my asthma! I went from using my inhaler more than I have in awhile (and taking quercetin recommended by my naturopath with very little relief) to now using nothing but DMSO and feeling like my chest has opened entirely and I can take entire deep breaths! I went on a walk this morning and cruised up rather steep hills without barely any increase in my respirations! That never happens. Usually I’m huffing and puffing and my chest is super tight. The palpitations have also disappeared.
The DMSO I’ve been taking for my asthma is night and day. I can breathe! 😊
I’ve been using [DMSO] a week and am feeling fantastic overall and my asthma is non existent right now. I was really struggling with it lately before starting this. Energy too is coming back
Greetings! I’m 59 years old. I’ve had asthma since my early teens which gets set off by my allergies. Within days of starting to take 1 tablespoon of DMSO per day, I was able to use my albuterol inhaler less. Now it’s been months since I last used it. I used to need an inhaler every time I played table tennis, but now never. I feel less sensitive to dust, although certainly not cured.
I inhaled DMSO spray accidentally when making a castor oil pack. The vapors filled up the room and I left the room asap as I thought it would be dangerous to inhale. I was having some difficulty with asthma. That evening my lungs were completely cleared. Who knew! 😊
I’ve been using DMSO since November 2024 (big improvement in veins and circulation. That is helping my severe asthma amazingly.
My nephew, a welder, started using dmso for his hands. The pain subsided. He suffered with severe asthma. He discovered soon after that he wasn’t using his inhaler any longer.
My grandpa had horrible asthma, he started nebulizing DMSO in the early 90’s and he no longer needed rescue inhalers. Lived till 94, survived multiple strokes with no side effects, and amazed doctors by how quickly he recovered. He always said it was the DMSO
I have asthma and [inhaling DMSO] was really helped.
I started using it for my asthma. I feel so much better..
DSMO has greatly helped my asthma. 👍
I get pains with asthma and DMSO usually relieves the pain
I apply it topically to my chest to help asthma.
Including one lovely one about an old cat:
My 20 yr old cat developed a cough which the vet diagnosed as asthma. He wanted to put her on an inhaler, but I had my doubts that she would tolerate that. So I tried using DMSO on the back of her neck…No coughing at all. Amazing stuff.
Data supports these accounts:
Numerous studies have found DMSO increases the potency of steroids (a mainstay of asthma and COPD treatment), making it possible for much lower doses to be used.1,2,3.4 As steroids often have significant toxicity (particularly when used at high doses for prolonged periods), this can be quite useful.
Treating Sinus Conditions
I started to use [DMSO] to see if I could control my sinusitis…My sinusitis improved almost from day one, I no longer feel the mucous running at the back of my throat and, in the morning, I don’t experience anymore the intense coughing I used to have everyday.
It is incredible. I treated my 4 day very serious sinus/cold/flu this week and it was the only thing that helped. I even nebulized peroxide, iodine, and silver before that. The DMSO was a lifesaver.
As more people have begun experimenting with nebulization (which must be done at a low dose), I will review the existing protocols for using DMSO below.
Sourcing Best DMSO Products:
I’ve frequently received many questions about the best brands of DMSO to use. I believe that these are the three best options (and I’ve included Amazon links).
Note: unless you feel confident in diluting them correctly, opt for the 70% dilution, as that concentration typically works for most people. When buying liquid DMSO, I believe it should always be sold in a glass container unless the plastic container is DMSO resistant and likewise has a DMSO resistant cap. If you buy gel, it’s okay if it’s sold in plastic.
• Jacob Lab has a full range of products and dilutions (e.g., this 70% gel or this 70% liquid) –is 99.98% pure. Jacob lab offers both glass and also plastic they claim is DMSO resistant- it likely is, since Stanley Jacob’s son runs the company, and from talking to him, we know he is very dedicated to continuing his father’s work).
• The DMSO Store (e.g., this 100% gel or this 100% liquid or this 100% spray, coming soon (which you might want to dilute first)—can also be bought directly from www.DMSOStore.com)— is 99.995% pure (and hence often the most popular for internal applications). Note: dmso.store is a completely different company than dmsostore.com.
• Nature’s Gift (e.g., this 70% gel or this 70% liquid)—which is 99.9% pure.
• [I, Jacqueline, want to interject that we personally use this USA-produced PharmaDMSO product for oral use because it is triple filtered to 0.22 which removes any garlic odor often associated with DMSO. It’s very gentle on my stomach and my husband’s at 100% (undiluted). It is in cobalt blue glass containers, and I believe the highest quality product available.]
Note: Local sources of DMSO (e.g., from Tractor Supply) are more than good enough for people’s immediate needs (say, an injury), but NOT ideal when preparing DMSO combinations (rather, I prefer the higher purity options available above).
DMSO Dosing:
One of the challenges of using DMSO is that there’s significant variation in what each individual best responds to.
There is a very small risk (1 in 1-2000) of an allergic reaction, so it’s generally advised to begin by patch testing DMSO on the skin before taking it orally. *If used topically, some individuals may experience itching, tingling sensations, and irritation for the first few times, which are normal. If you experience any signs of an allergic reaction (e.g., swelling), wash the affected area and discontinue use. (Please know that it does not actually harm you cellularly, but for some it can feel uncomfortably hot.)
How to Patch Test:
• Select a Small Area: Choose a discreet spot.
• Apply a Tiny Amount: Use a small quantity of the product.
• Wait and Observe: Leave it on for 24 hours unless you notice irritation sooner.
• Proceed if All’s Good: If no reaction, feel confident in using the product as intended.
Because of this, you essentially have two options, and have to decide which is right for you:
1. Be patient and start with a low dose that you can build up.
2. Start with a stronger dose and agree not to hold it against me or DMSO if you don’t tolerate it.
In my previous articles, I’ve advocated for #1. Still, many understandably started with a high dose as they did not want to wait for the results, a few of whom then shared they’d had a skin reaction that made them hesitant to continue using DMSO.
Administration – Oral and Topical
When using DMSO, there are two common routes of administration: oral and topical.
Topical Use:
1. I typically suggest starting with topical DMSO before taking oral DMSO. For more systemic issues (e.g., joint pain throughout the body or low energy), oral administration is often necessary (and in many cases works well if done in conjunction with topical DMSO).
2. Start with 30-50% topical DMSO and see how you tolerate it. When applying to the face, ensure that all makeup has been thoroughly washed off (ideally you have been using only natural cosmetic and skincare products) and use a lower concentration (~20%). I had one reader who started with a 70% gel on the face and contacted me about a reaction they had (although after the surface layer of skin peeled off, her face underneath did look much younger).
You can use a liquid directly applied with your fingers or an organic cotton facial pad. A gel is simply rubbed into the skin.
3. If you have no issue, gradually raise it to 70%. People rarely react to 70% topically and is the best balance between safety and efficacy.
4. Only raise it topically past 70% if you are certain you are one of the many people who is fine with 100%.
Oral Use:
5. For oral dosing, start with a (1) teaspoon of 70% or 100% DMSO mixed into a glass of water (you may also want to add juice to eliminate any DMSO taste).
6. If you experience issues with that, try lowering the dose to half a teaspoon in water.
7. Otherwise, stay at (1) teaspoon for at least three days, and then if you think you need a stronger effect, go to 2 teaspoons.
8. Consuming more than 3 teaspoons of liquid in a glass of water is excessive. At that point, it is best to divide the dose throughout the day.
9. With both topical and oral DMSO, people generally find that their tolerance to it IMPROVES over time.
10. Conversely, if used too frequently a tolerance can develop, so it’s typically advised to take it only 5 days a week.
The key point is that everyone has a different tolerance to DMSO.
Higher doses are often more effective (and many users use 100% undiluted without any issues whatsoever), still, it’s best to start with a low dose and be patient.
Dilution Options, Including For Different Areas of the Body
• You can apply 70% topically as it is, or mix it with equal parts of purified water to get it to roughly 35%.
• You can also do this with 100% DMSO. Dilute it to roughly 50% by mixing it with equal parts of purified water – or to roughly 33% by mixing it with two parts of purified water.
I personally prefer the liquids because it’s easier to control the total dose with them, more gets into the body, and liquid DMSO tends to be less irritating. Gels hold the advantage of continually releasing DMSO into the body over a prolonged period and are much easier to apply. As a result, the choice you make is largely a matter of personal preference.
As mentioned above, when applying topically, it is essential first to clean the area to which it will be used.
This is a general guideline on whats appropriate for each part of the body:
External Use (Skin) Concentration:
• Legs/Feet: 50–80% (70% typical).
• Arms/Torso/Neck: 40–70% (50% typical).
• Head/Face: 25–35%. (some go up to 50% for the head)
• Wounds: 40–60%.
• Warts/Boils: 75%.
• Sensitive Skin/Face: Start at ~20-25%.
Application: 2–3 times daily, adjusted based on skin sensitivity and response.
Precautions: Avoid >15% on surgical stitches to prevent brittleness.
For Mucous Membranes:
• Mouthwash for gum issues/inflammations: 5–15% solution, swish for 2–4 minutes (can go higher if no dental implants).
• Ear/Nose Drops: 15–40% (15% minimizes irritation).
• Other (e.g., oral, rectal, vaginal): As low as 10% due to high tissue permeability.
• Cold sores: Dab directly (often with 100% DMSO).
Dilution of DMSO With 0.9% Saline For Sensitive Areas & Nebulizing
For more sensitive parts of the body (eyes, colon, oral mucosa, or lungs, etc.) it is often quite helpful to dilute it with isotonic, 0.9% saline (which can be prepared at home by following the 3rd paragraph in this image) (and it is widely available) so it is gentler (although many do not do this and are fine).
Respiratory Protocols
Asthma frequently responds to topical DMSO (often 30-60%) applied to the chest over the lungs, orally, or nebulized. Most of my readers have achieved success without nebulizing it from this approach. One reader shared that the best relief comes from applying DMSO in the morning after a shower and at night before going to bed.
One common asthma protocol involves nebulizing 5-10 drops of DMSO in a 20 ml (approx 4 teaspoons) of 0.9% saline solution.
Pulmonary fibrosis appears to respond best to high oral DMSO doses (e.g., 3 teaspoons diluted in water, 1-2 times a day), but there are also numerous reports of topical or nebulized DMSO being beneficial.
COPD responds best to nebulized DMSO, but also responds to topical and oral.
Pneumonia and lung infections require nebulized DMSO, preferably mixed with an antimicrobial agent, of which chlorine dioxide is the most preferred, followed by colloidal silver and hydrogen peroxide. When using either CDS or hydrogen peroxide, as they slowly oxidize DMSO (and get reduced in the process), it is important to prepare them immediately prior to application. I typically recommend Argentyn 23 for anyone wishing to nebulize colloidal silver.
Note: nebulized CDS and hydrogen peroxide combinations will be discussed further in the next DMSO article I am working on.
Nebulizing DMSO
I have seen a very wide range of concentrations people use to nebulize DMSO (e.g., a few drops in a nebulizer, 1%, or 5-10%). The community I feel is the most knowledgeable about DMSO advocates for 1% nebulization (and often just has a few drops in the nebulizer), whereas some DMSO authors suggest higher concentrations (5-10%).
With DMSO and nebulizing, there are a few very important considerations.
First, many nebulizers are made of easily dissolvable plastic. For this reason, you will likely have one that cannot tolerate higher DMSO concentrations, and a few readers have reported discovering that DMSO dissolved their nebulizer’s plastic. As such, this again suggests the use of low concentrations meaning IT IS DILUTED to 1% or 5%. Fortunately, the concentrations used for nebulization (e.g., 1%) are far below those that leach (typically 15-20%).
Second, if a too high DMSO concentration is used, the lungs will “burn.”
Third, when nebulizing, DMSO should be dissolved in an isotonic, 0.9% saline solution (which can be prepared at home by following the 3rd paragraph in the image above with yellow highlighter) (and it is widely available pre-made online) .
Fourth, some also find that nebulizing dilute hydrogen peroxide, or silver very helpful. I have read many reports of these combined with DMSO creating miraculous cures for conditions like Asthma or COPD, but DMSO alone may have also worked. When this is done for non-infectious conditions, it’s often advised to alternate between one and the other.
Fifth, a theoretical risk exists for DMSO (over 10%) interfering with the surfactant coating the inside of the lungs. For this reason, especially in individuals with compromised respiratory function, it is advisable to go slowly and monitor one’s respiratory capacity during the process (e.g., with a pulse oximeter). I think it’s more likely than not this is not an issue, particularly since there are a lot of reports on alternative health forums of remarkable results with 1-5% nebulized DMSO (e.g., for COPD, pneumonia, bronchitis, reducing lung inflammation, and removing microbial infections), and I’ve not come across any adverse ones).
Always, DMSO should be nebulized at low doses.
Conclusion
I feel incredibly blessed that a remarkable confluence of historical events is finally making it possible to bring this forgotten aspect of medicine to the public. If people can achieve miraculous results from easily available treatments that greatly exceed the standard of care, they will share their experiences with others. Especially in the post-pandemic climate we live in, many will listen. Thank you. ~The Midwestern Doctor
You can read more about The Midwestern Doctor here. His Substack site The Forgotten Side of Medicine is rich and useful, though very lengthy.
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Medical Disclaimer: I am no longer a practicing medical professional, and I am not doctor. I am a mother. I do seek scientific confirmation of the safety and effectiveness of the herbs and remedies I use. Using remedies is a personal decision. Nothing I say on this blog is intended to treat or prevent disease. Consult your own doctor.
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