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The Value of Methylene Blue & How To Keep It From Staining Teeth

16.3KViews Modified: Mar 16, 2026 · Published: May 10, 2023
By Jacqueline 16 Comments

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The Value of Methylene Blue & How To Keep It From Staining Teeth

Since it was first isolated as a chloride salt compound in the late 1800s, methylene blue (MB) has demonstrated a very wide range of therapeutic benefits, including calming antidepressant effects and neuroprotectant properties resulting in enhanced memory and relief for Parkinson’s. It also was used to treat malaria for nearly 100 years, but it fell out of favor when chloroquine, a quinolone-based drug, emerged on the scene.

It is also well-known to zap viruses including Hepatitis A and C, HIV, Ebola, Zika, West Nile, Dengue and Covid-19, and it boosts ATP levels (the energy-carrying molecule found in the cells of all living things). You can read the details in my 2 blogs here.

In recent years, researchers have begun to look at Methylene Blue (1%) as an antimicrobial agent against Lyme disease and as a treatment for persistent Bartonella. Because it isn’t an antibiotic, it does not destroy the gut flora like synthetic antibiotics do. 

Note: Methylene Blue 1% has been SOLD OUT on Amazon and other sites for quite a while. I made a way to get my readers 10% off using this special link directly from Compass Laboratory: Methylene Blue (1%). Use the coupon code: Deeprootsathome

I’ve had many ask me how to use MB without staining mouth and teeth. Here is what we do in our family.

How to Reduce Methylene Blue So It Can’t Stain Your Teeth or Skin

Though it is safe to take more than this (see chart here), my husband and I personally consume 10 drops of Methylene Blue (1%) , usually 1x/day. To take away MB’s ability to stain, we follow a little routine:

1.  Add only an inch or 2 of purified water to your glass.

2.  Then add your Methylene Blue (1%) to that glass. (You can see the low dose chart per body weight here)

3.  Next, add 1 g. (1,000 mg.) of buffered sodium ascorbate powder (Vitamin C) to the water.  Understand, that the more drops of MB you use, the more vitamin C you will need to reduce the color. There is no danger in taking these amounts of vitamin C. Since I want to be more alkaline, I also add a good splash of organic lemon juice to this mix.

We now know that Vitamin C taken together with Methylene Blue enhances the absorption and function of MB.

4.  It will take a minute or so for it to reduce to a pale turquoise color. If you are patient, you will find you can use less vitamin C.

5.  Lastly, chug it down. We find MB to be essentially tasteless and not objectionable. We’ve never had stained teeth or mouth, but if you’re not careful, you could stain your hands or counter. A little lemon juice or dissolved Vitamin C and time will resolve the matter.

The Value of Methylene Blue & How To Keep It From Staining Teeth

Ten (10) drops of MB 1% equals 5 mg/day. Very low doses like this are discussed at 1:02:30 in the video below.  Yes, your urine will be blue-green-tinged, but observing that tells you when your levels are low again. The half-life is 12-13 hours. 

In this video, Dr. Mercola and Dr. Francisco Gonzalez-Lima cover why Big Pharma doesn’t want us to know about Methylene Blue (1%) or how to use it – even though every hospital in the world has it and it is an essential medicine according to the WHO.. If you want to care for your family outside of the present medical paradigm, this would be something to pay attention to and have in your medicine toolkit and know how to use it.

[Gonzalez-Lima is the top world expert on Methylene Blue (1%) , which helps mitochondrial respiration and improves brain energy metabolism that can truly prevent neurodegeneration and improve cognitive performance. “Our group was the first to map the effects of methylene blue in the brain of humans and show its effects on improving brain metabolism, blood flow and memory function.”]

The first 10 minutes cover a lot, and at 1:13:00, he mentions using Vit C to reduce the deep color and prevent staining.

Low doses of MB work well as a nootropic (a supplement that enhances cognitive performance), but high doses DO NOT. 

Very low dose Methylene Blue (1%) supplementation (0.5 mg to 1 mg/kg of bodyweight/day) provides many life-enhancing effects, while very high doses are harmful. With MB, less is more.

Note: Methylene Blue 1% has been SOLD OUT on Amazon and other sites for quite a while. I made a way to get my readers 10% off using this special link directly from Compass Laboratory: Methylene Blue (1%). Use the coupon code: Deeprootsathome

For more information, contraindications, or TO SEE THE LOW DOSE CHART PER BODY WEIGHT, go here. Follow directions closely or find and consult a functional doctor before use.

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The Value of Methylene Blue & How To Keep It From Staining Teeth

Medical Disclaimer: I am no longer a practicing medical professional, and I am not doctor. I am a mother. I do seek scientific confirmation of the safety and effectiveness of the herbs and remedies I use. Using remedies is a personal decision. Nothing I say on this blog is intended to treat or prevent disease. Consult your own doctor.

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Hi! I’m Jacqueline!

Thanks for being part of this journey with me.
Welcome to my own little place on the internet! Home is where I love to be. I feel there is no greater place to incubate souls. These days you’ll find me using my experiences here to write about herbal remedies and natural health research — a big passion of mine. But being a wife and mother is not easy. It is challenging and potentially lonely. I get that. I wanted to create a place to connect with and support other moms for creating a natural, healthy, and fulfilling home life.
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Reader Interactions

Comments

  1. Danae

    May 11, 2023 at 5:26 am

    This is such an important post. I had Herpes which seem to start to attack the nerves and some part of my brain. Nothing helped. Even with the best food, some foods triggered for 5 years I had recurring herpes outbreaks. I took high amounts of Vitamin C (based on doctoryourself by Andrew Saul and the Orthomolecular medicine) and was able to completely heal from the nerve damage pain in my leg! That was phenomenal as allopathic medicine claims nothing can cure the nerve damage. However, here was still a strange feeling (no pain though) in my brain.
    I recently decided to take MB (Methylene Blue) like you 10 – 15 drops and felt that it brought something in my brain “online”. Yet, the most wonderful outcome is that I had not a single herpes recurrence since – even though I did eat trigger food (mainly certain nuts, eggs etc). It has been 2 1/2 months now and I feel it still gets “better”. This is all purely anecdotal, yet, I know though my own healing path that anecdotes have sometimes got me further than official studies. Just like curing my nerve pain – according to studies there was no cure.
    However, we traveled a few days with a vaxxed friend (who had the shot that with magnetic properties) and I got Covid for the first time in all these years! It was definitely shedding. It was a real attack on my nervous system and MB did not “protect” me seemingly. I was a bit disappointed at first. However, I got though the attack in 3 days – whilst my partner not taking MB had 7 days extreme symptoms and even after 4 weeks still got occasional fever (we both took the same supplements NAC, Spermidine, High doses of Vitamin C, D3/K2, Magnesium, Zinc, Selen, Quercitine etc.). The only difference was that I took MB and now I think whilst it did not stop the attack from shedding it seemed to allow my body to recover far quicker.
    With regards to the blue tongue. I just take a chaser of grapefruit juice or juice with lemon and never have any stained teeth. But your idea to add Vit C immediately is even better. MB is amazing and is definitely in my medicine cabinet. Thank you.

    Reply
    • Jacqueline

      May 11, 2023 at 10:22 pm

      Danae, thank you for sharing your story with me (and with us)! And I pray more people will consider MB as it has SO much to offer on so many levels!
      I do believe that shedding of the ‘vac’ is a real thing and that it has affected me as well. I consider MB as a permanent part of our medicine chest, esp since we had prions in the past.
      https://deeprootsathome.com/is-there-an-antidote-for-prion-protein-damage-from-the-spike-protein/
      With TRS and MB, I believe we have a lot of bases covered!

      Continued blessings,
      Jacque

      Reply
    • Nelson

      November 26, 2024 at 6:31 pm

      Dear Danae, your stack you’re taking is a very good one. I would just add ivermectin, BCM-95 Bio-Curcumin for any shedding or covid related illnesses. DMSO and Lysine for herpes and cold sores. AMD mentioned DMSO for herpes in his article. Iodine for overall health.
      God bless.

      Reply
  2. Joy

    May 24, 2023 at 12:20 pm

    Hi Jacque, have you heard of putting MB on your skin? I’ve heard great reports of using it in a facial skincare routine with moisturizer for cell renewal and regeneration, and would love a recipe for how to make a DIY version. I am currently just buying a brand online but it’s spendy. I tried adding MB to my own moisturizer but even one drop turns it blue (obviously), which then turns the skin blue (yikes!). I know there must be a way to get the benefits of MB on our skin without turning it blue, so if you know of any DIY skincare recipes please do a post on it! Blessings

    Reply
    • Jacqueline

      May 28, 2023 at 11:20 pm

      Joy, I need to do some experiments and see what I can come up with! If I find something that I feel is worth writing about, I certainly will!
      Thanks for asking and expressing interest in it!
      Blessings,
      Jacque

      Reply
      • Joy

        May 29, 2023 at 11:34 am

        Thank you so much Jacque! You’re such a blessing!

        Reply
  3. Nana’s Girl

    June 02, 2023 at 8:04 am

    Loved seeing this post – thank you! Having been plagued by frequent UTI’s over the years, I started taking methylene Blue about a year ago with great success as a preventative / early treatment. Dr. Gonzalez-Lima talks about how it was used OTC in America in capsule form to treat UTI’s until antibiotics came out in the 60’s – 70’s. I’ve taken so many antibiotics for UTI’s over the years that my gut health was not good, and I can’t supplement with NAC, Vitamin D, etc., because I get diarrhea. I took 10-12 drops in water every day for close to a year. I did notice that it was an irritant to my bladder (as it is supposed to be in sterilizing the bacteria) so I stopped the daily use. My doctor prescribed me 15 mg capsules of powdered Methylene Blue from a compounding pharmacy, so that I can easily take a higher dose when I’m developing a UTI – without the mess of the liquid MB. Works very well with just one or two doses. The OTC capsule years ago was 60 mg!

    Reply
    • Jacqueline

      June 02, 2023 at 12:01 pm

      Wow, this is such great information for us to have, Nana’s Girl!
      I appreciate you sharing it here for other’s to learn from.
      MB is truly a wonderful help and needs to be more widely known~

      Blessings to you,
      Jacque

      Reply
  4. honingbij

    November 04, 2023 at 4:39 pm

    Hi Jacque:

    You mentioned only putting 1/2″ water in the glass [about 100 ml by my reckoning] and no more.

    Is more less desirable in some way?

    Also is there an upper limit to the amount of vitamin C that can be put into the glass to make the solution lighter?

    Thanks for any further information!

    Thanks for any information!

    Reply
    • Jacqueline

      November 04, 2023 at 9:43 pm

      Hi, Honingbij,
      I just went into the post and changed that to an inch or so of water. That is just so that at first, you have a more concentrated solution to add the vit C to.
      Once the blue color is gone, then you can add as much water or juice, etc to it as you wish. And the vit C isn’t so noticeable.
      I hope that helps,
      Jacque

      Reply
      • honingbij

        November 05, 2023 at 4:05 am

        Thanks so much!

        Reply
  5. Kendra

    May 16, 2024 at 8:36 am

    Hello!
    I just wanted to come on and add to all the wonderful comments here. So many great uses for “blue”. Over the winter I noticed I was getting a small rash around the cup line of my bra. I thought it was dry skin and so I put more lotion on it. Long story short and many months of the rash getting worse…my full chest, neck and arms…I was at my wits end with itching, burning and pain. Come to find out it was fungal. Once we, my natural path and myself figured out it was fungal she immediately told me to start on the “blue”. It turned everything around! Praise God!! I also started researching it for myself and learned that even in mainstream medicine they are using it for fungal rashes all over the world and that it is the only thing that has about an 80-90 percent cure rate. Thank you Jackie for all you do. I share your posts with friends and family all the time.

    Reply
  6. Hope

    July 03, 2025 at 7:44 am

    Hi Jacque…
    I just recently ‘stumbled’ across a post that mentioned Methylene Blue and all of the health benefits. I found it in a cancer post but, the lady that posted mentioned how much it helped her Mom with dementia. My sweet Mom has recently been placed in a nursing home due to Alzheimers/Dementia and my heart breaks for her every day. She feels like she is in prison but can’t understand why or what she did that was so terrible to deserve being there. Her mind is so scattered with the disease and, I think, some of the meds they are giving her only make it harder for her. Can you tell me if MB has any contraindications with any medications..?

    Also Jacque…someone mentioned that MB comes in a pill form..? Is the pill as effective as the liquid drops..? I’m thinking pill form might be an easier route for Mom in her current state…IF she will take it.

    Thank you so much for any information.
    Have a beautiful day! 🙂

    Reply
    • Jacqueline

      July 03, 2025 at 9:01 am

      Oh, Hope, my heart breaks for you and your Mom in this situation! Yes, Methylene Blue can be transformative, but it depends on how far she is into dementia. I have several posts on it, but this is the most important for you!\
      https://deeprootsathome.com/methylene-blue-memory-mood-parkinsons-adhd/
      There is also this on what else it can do: https://deeprootsathome.com/methylene-blue-inactivates-hiv-hepatitis-ebola/
      I am not sure if it comes in a capsule, but let me look now…
      Okay, there is one but it is much more expensive than the regular drops. A whole bottle of the drops is $30. and lasts 6-10 months depending on how much one takes, but it will be much easier for her if she has to take it herself. She can start with 1/d and then start taking 2, split AM and PM, as she works up!
      Look into this: https://amzn.to/4kisa5l
      How often do you see her? I have some other ideas to help her if you see her several times a week. Email me at [email protected]
      God bless you as you serve your dear Mama!
      I am praying for you both now!
      Jacque

      Reply
  7. Debbie

    March 14, 2026 at 10:00 am

    Hi Jacque. If my husband and I start taking this, should we start out with one drop a day and work up to 10? Also, do you ever take a break from it? Thanks.

    Reply
    • Jacqueline

      March 14, 2026 at 2:08 pm

      Hi, Debbie, 🙂
      We started out at 5 drops (very, very low) once a day and in a couple weeks went to 10 drops a day, but I don’t think it matters. During the height of Covid, particularly on Sunday being around people we knew who boosted, my husband and I did 10 drops twice a day to provide greater protection. That is still a very low amount – many do far more, but we aren’t comfortable with that. We have not used MB for months now but certainly will again as needed. Also, during surgery, I recommended not to use it just out of an abundance of caution.
      I hope you are well! Blessings,
      Jacque

      PS:
      This dosing chart is only for reference of what is in the safe range. However, most will find the following amounts are not needed to get the wonderful effects
      You will find this chart (and the source for it) here: https://deeprootsathome.com/methylene-blue-memory-mood-parkinsons-adhd/
      DOSING FOR METHYLENE BLUE 1% SOLUTION

      Body Weight: 50 kg/110 lbs: 0.5 mg/kg dose = 25 mg/day or 50 drops/day

      Body Weight: 55 kg/121 lbs: 0.5 mg/kg dose = 27.5 mg/day or 55 dr/day

      Body Weight: 60 kg/132 lbs: 0.5 mg/kg dose = 30 mg/day or 60 drops/day

      Body Weight: 65 kg/143 lbs: 0.5 mg/kg dose = 32.5 mg/day or 65 dr/day

      Body Weight: 70 kg/154 lbs: 0.5 mg/kg dose = 35 mg/day or 70 drops/day

      Body Weight: 75 kg/165 lbs: 0.5 mg/kg dose = 37.5 mg/day or 75 dr/day

      Body Weight: 80 kg/176 lbs: 0.5 mg/kg dose = 40 mg/day or 80 drops

      Body Weight: 85 kg/187 lbs: 0.5 mg/kg dose = 42.5 mg/day or 85 dr/day

      Body Weight: 90 kg/198 lbs: 0.5 mg/kg dose = 45 mg/day or 90 drops/day

      Body Weight: 95 kg/209 lbs: 0.5 mg/kg dose = 47.5 mg/day or 95 dr/day

      Body Weight: 100 kg/220 lbs: 0.5 mg/kg dose = 50 mg/day or 100 drops/day

      Reply

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