Besides totally inactivating HIV-1, Hepatitis A and C, and the Ebola and Zika viruses, Methylene Blue (1%) is scientifically proven to be neuroprotective and help restore/reset brain function in people with Alzheimer’s, Parkinson’s, bipolar, depression and more.
Existing ‘approved’ drugs for dementia obviously don’t work or they would be curing people and the disease would disappear.
Methylene Blue (1%) is the parent molecule for hydroxychloroquine, the off-patent drug commonly used to treat not only malaria but also “The Great Flu”. Until antibiotics came along, it was commonly used to treat urinary tract infections (which still works, btw) at low doses mentioned below. It’s also used as an antiviral agent in blood transfusions.
To this day, Methylene Blue (MB) is found in every hospital worldwide for metabolic poisons that interferes with oxygen transport. If you’re admitted for carbon monoxide or cyanide poisoning, you’ll receive methylene blue intravenously. It’s the only known antidote.
Studies have demonstrated Methylene Blue (1%) is an extremely effective antidepressant. You likely don’t know about it because very this affordable substance would put the mental health industry out of business. And it doesn’t have the nasty side-effects of Paxil or other antidepressants.
In this video, Dr. Mercola and Dr. Francisco Gonzalez-Lima cover why Big Pharma doesn’t want us to know about Methylene Blue (1%) or how to use it. If you want to care for your family outside of the present medical paradigm, this would be something to pay attention to and have in your medicine toolkit.
[Gonzalez-Lima is the top expert on Methylene Blue which helps mitochondrial respiration and improves brain energy metabolism that can truly prevent neurodegeneration and improve cognitive performance. “Our group was the first to map the effects of methylene blue in the brain of humans and show its effects on improving brain metabolism, blood flow and memory function.”]
The first 10 minutes cover a lot, and very low dosage is discussed at 1:02:30.
Low doses of MB work well as a nootropic, but high doses DO NOT. See the low dose chart below.
Quick list of important neurological diseases Methylene Blue addresses:
Methylene Blue for Bipolar Disorder:
MB in the Treatment of Neuropsychiatric Disorders. Conclusion: “Use of methylene blue in bipolar disorder led to a better stabilization and a reduction in residual symptoms of the illness.” Another study here. See MB May Help Bipolar Depression.
Methylene Blue for Depression
A Controlled Trial of MB in Severe Depressive Illness. Conclusion: “Methylene blue at a dose of 15 mg/day appears to be a potent antidepressant..”
The Prophylactic Effect of MB in Manic-Depressive Psychosis. Conclusion: “During the year the patients were treated with methylene blue at 300 mg/day, they were significantly less depressed than during the year on 15 mg/day.”
The Journal of Neurotrauma reports that methylene blue has an antidepressant effect in mice with traumatic brain injury (TBI).
MB Resists Alzheimer’s, Dementia, Parkinson’s, and Huntington’s Diseases
MB and Alzheimer’s Disease. Conclusion: MB is known to reduce the formations of amyloid plaques and neurofibrillary tangles and to repair impairments in mitochondrial function and cellular metabolism. It also shows promise in treating Parkinson’s and Huntington’s diseases... (source)
MB Improves Memory:
Neurometabolic Mechanisms for Memory Enhancement and Neuroprotection of MB. Conclusion: “..Methylene Blue is neuroprotective… a safe intervention for the treatment of acute and chronic conditions with neurodegeneration and memory impairment.”
Functional MR Imaging of the Effects of MB in the Human Brain. Conclusion: “A single oral dose of MB improved memory retrieval by 7% and increased MRI-based responses in areas of the brain that control short-term memory and attention.”
More supporting studies here, here, here, and here.
MB Boosts Acetylcholine Important for Neuroplasticity
MB inhibits problematic acetylcholinesterase activity; the outcome is increased levels of acetylcholine. Acetylcholine’s function in the brain is critical for encoding new memories, reasoning, concentration, cognition, and growth of new synapses (neuroplasticity). Lack of acetylcholine can result in diseases like ADD, ADHD and Alzheimer’s. MB improves serotonin and norepinephrine affecting anxiety, depression and memory.
MB Increases Mitochondrial Energy:
Methylene Blue assists brain cell respiration by increasing oxygen. And donating electrons to the electron transport chain within mitochondria. This same process is used to create ATP within mitochondria from the food you eat. So MB contributes to this energy-production process. Increasing cellular energy positively effects mood and memory.
MB is Neuroprotective:
Methylene Blue (1%) is a potent antioxidant. When damaging reactive oxygen species are produced inside mitochondria, the first free radical that is formed inside a cell is superoxide. MB will bind to superoxide and reduce it to water. It stops the oxidative cascade at its very beginning, before it gets a chance to do damage.
Note: Methylene Blue 1% has been SOLD OUT on Amazon and other sites for quite a while. I made a way to get my readers 10% off using this special link directly from Compass Laboratory: Methylene Blue (1%). Use the coupon code: Deeprootsathome
How to Take Methylene Blue
Very low dose Methylene Blue (1%) supplementation (0.5 mg to 1 mg/kg of bodyweight/day) provides many life-enhancing effects, while very high doses are harmful.
With MB, less is more.
Make sure to get it from a trusted source. The 1% product is 0.5 mg./drop and batch tested for purity.
REMEMBER: Very low dose Methylene Blue (1%) supplementation (which is 0.5 mg/kg of body weight/day) provides many life-enhancing effects, while very high doses (2 mg/kg. and above) are harmful. To get good effects, you can take a fraction of these recommended low levels and still get good effects. I always recommend talking with your functional doctor.
Note: Methylene Blue 1% has been SOLD OUT on Amazon and other sites for quite a while. I made a way to get my readers 10% off using this special link directly from Compass Laboratory: Methylene Blue (1%). Use the coupon code: Deeprootsathome
This dosing chart is only for reference of what is in the safe range. However, most will find the following amounts are not needed to get the wonderful effects.
DOSING FOR METHYLENE BLUE 1% SOLUTION
Body Weight: 50 kg/110 lbs: 0.5 mg/kg dose = 25 mg/day or 50 drops/day
Body Weight: 55 kg/121 lbs: 0.5 mg/kg dose = 27.5 mg/day or 55 dr/day
Body Weight: 60 kg/132 lbs: 0.5 mg/kg dose = 30 mg/day or 60 drops/day
Body Weight: 65 kg/143 lbs: 0.5 mg/kg dose = 32.5 mg/day or 65 dr/day
Body Weight: 70 kg/154 lbs: 0.5 mg/kg dose = 35 mg/day or 70 drops/day
Body Weight: 75 kg/165 lbs: 0.5 mg/kg dose = 37.5 mg/day or 75 dr/day
Body Weight: 80 kg/176 lbs: 0.5 mg/kg dose = 40 mg/day or 80 drops
Body Weight: 85 kg/187 lbs: 0.5 mg/kg dose = 42.5 mg/day or 85 dr/day
Body Weight: 90 kg/198 lbs: 0.5 mg/kg dose = 45 mg/day or 90 drops/day
Body Weight: 95 kg/209 lbs: 0.5 mg/kg dose = 47.5 mg/day or 95 dr/day
Body Weight: 100 kg/220 lbs: 0.5 mg/kg dose = 50 mg/day or 100 drops/day
How To Make It NOT SO BLUE
(Jacque’s note: I personally consume 10 drops of this Methylene Blue (1%) into 1-2″ of lemon water (and add 1-2 gms. of buffered sodium ascorbate powder, too) both AM and PM, and wait a few minutes till the blue color lessens dramatically. That VERY LOW DOSE is a total of 20 drops/day or 10 mg/day. Very low doses like this are discussed at 1:02:30 in the video above. I use a straw, swish with pure water afterward and have not had stained teeth. Urine will be blue-green-tinged, and observing that is helpful to tell you when your levels are low again. The half-life is 12-13 hours.)
Contraindications:
Do not use Methylene Blue if you have a G6PD deficiency, a liver or kidney disorder, if you regularly use 5-HTP or St. John’s Wort, or if you are pregnant or breastfeeding.
Side effects with MB are very rare when doses are under 2 mg/kg.
Monoamine Oxidase (MAOI) inhibition becomes a big problem over 2 mg/kg of MB. So if you are using antidepressants or anti-anxiety medications that affect dopamine or serotonin, you should NOT use Methylene Blue over 2 mg./kg.
NO MB during pregnancy or while nursing.
Note: In the video above, at 1:33:30, Mayo Clinic said there is “NO contraindication for oral MB with SSRIs”.
Follow directions closely or find and consult a functional doctor before use.
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Shirley
Thank you. I’m going to very carefully give this a try!1🙂
Jacqueline
Hi, Shirley,
We are doing 20 am and 20 pm (you may have read that) and it is sitting very well with us. We are 70 and 71, so want to stay on top of all things mental Haha 😀
Praying for you now!
Sending peace,
Jacque
Laura in Ontario
This is really interesting, and I’d love to give it a try, since I have CFS which comes with serious brain fog…some days my brain fog gets so bad I can’t understand how to read recipes I’ve made dozens of time before…as well, I don’t know the cause of my CFS, but it’s probably due to some chronic viral infection. Therefore this substance sounds like it could help me a lot. The only problem is the expense. The little bottle you have pictured is $30 US on Amazon, plus more to ship to Canada…according to the dosage for my weight, I would need to take about 80 drops per day, and I’m guessing I would use up that small bottle in only a couple of weeks…Do you think if I tried taking just a few drops per day it would still have an effect? I really would love to try it but my finances are just so strained right now.
Jacqueline
Hi, Laura, I sure do understand. That extra Canada upcharge is so high.
Did you see my note that We are doing 20 am and 20 pm, and doing very well with that? We are 70 and 71, have no brain fog, but want to stay on top of our mental wellness 😀
I think anything you can do to keep it from progressing is worth a lot… I always say with children’s training or our health, “pay now or pay later”, and in this case with that brain fog, I would do the max you can afford up to 1 mg/kg/day.
It probably costs the same shipping to get 3-4 bottles as one, but you could call the company and ask to know for sure. We do know the benefits of increased O2 is not permanent after stopping so longer term would be best, of course, but lower doses like we’re doing just makes sense cost wise too, and hopefully, you will have other side benefits IF hat you are dealing with is viral – we KNOW it is antiviral enough at low doses to inactivate covid (SARS), ebola, zika, smallpox, Hepatitis A and C, and shingles.
I am praying for you now.
Sending peace,
Jacque
Laura in Ontario
Thank you, especially for your prayers. I did not realize MB could also inactivate smallpox! That makes it all the more useful for us all to have on hand during these strange times we’re living in. Thanks so much for being such a constant source of useful information! God bless.
Katie
Laura,
A friend of mine pointed me to this Canadian source of methylene blue. I’m not sure, but I think if you order enough, shipping is free. Click on the blue question mark to find methylene blue.
https://lifeblud.co/
You would need to check the strength and adjust dosing as needed, not just go by the dosage in this blog post. They might be the same, but I haven’t checked yet.
Regarding shipping in general – We have ordered many things from small businesses in the US for many years and shipping has become very expensive, delayed, and more unreliable, especially in the last couple months. Shipping from Amazon.ca and bigger companies still seems quicker and more reliable.
Something we learned a couple years ago was that ordering in bulk from local health food stores often makes things more affordable. We usually get a discount when buying a full case of something. If that’s too much, you can partner w/ other families to split a case, etc. and everybody shares the savings.
I hope this info helps you!
Katie
Jacqueline
Katie, thank you for sharing your knowledge on the source for Canadian MB inlight of high shipping costs from the US.
I appreciate your input to help others! Hugs, Jacque
Christine
Hi! thank you for providing this information. I have ordered and received my first bottle. How long does it take to become effective? Is your recommendation for daily use; 20 drops AM; 20 drops PM? forever? I am a healthy 62 year old; still working full time; and active; hiking biking running etc. What differences will I experience?
Jacqueline
Hi, Christine,
Is is effective pretty much immediately upon taking and if you read the post has a 12-13 hour half life. When you stop, the benefits stop.
We are doing 10 drops AM and 10 PM right now bc we can feel the benefits even at that dosage and so why do more at this point. We would if we were vacc’d or if sick.
We are easily able to get out of bed in the morning without feeling exhausted and feel more cognitively motivated to attack our massive list to prepare for what is likely coming to our country.
Just more available and strong so that is probably due to the increased O2 to all our cells (incl. brain).
Not a recommendation, but what we are doing.
Blessings,
Jacque
Katie
Jacque,
I’ve been meaning to ask – would you please do a blog post about your complete supplement/meal routine? It’s difficult for me to wrap my mind around when you take all your various supplements/superfoods because you have so many different blog posts about the different ones you use (not to mention so many being added in for c o v i d and sp i k e pr o te in issues!). Some supplements are taken on an empty tummy, some w/ meals, some need to be taken a couple hours apart from others, etc.
We’re enjoying a beautiful weekend here! I hope you are, too.
Katie
Laura in Ontario
Jacqueline, I wanted to come back here and tell you that I did end up ordering the MB from Amazon.com. It arrived to me quickly and I tried it right away. I found the results were immediate. When I took the first dose of 10 drops, I felt a lessening of my extreme fatigue within about an hour. I have been taking it every day since then and it’s really making a difference with my CFS. I’m not saying that I’m cured, but it really makes things better for me. I’m now just tired instead of completely exhausted. Also, I found I have experienced less depression and anxiety since taking it and my mind seems clearer overall. So I’m very pleased with this product and I’m so glad you recommended it. Thanks so much.
I have a question though. Do you know if it matters when I take MB? i.e., should it be taken on an empty stomach, or with food, or does it matter? Is it okay if I take it with other supplements like herbs and vitamins? I want to be able to get the full effect which is why I’m asking. I assume taking something on an empty stomach usually works best.
Jacqueline
I do recommend (and I see others do, too) for best absorption and effects to take it first thing in the morning and sometime before bed.
I take it with my morning lemon water and salt sole.. https://deeprootsathome.com/honey-lemons-drink/
https://deeprootsathome.com/salt-sole-never-buy-minerals-again/
I am also seeing a sharper mind and easier writing with less anxiety over deadlines, etc.
I am so thankful to hear your testimony. Thank you for sharing it with us here 😀
Sending peace,
Jacque
Laura in Ontario
Jacqueline, I’m commenting again here to ask another question about Methalyne Blue. I’m continuing to take it at a low dose (no more than 40 drops per day, although my recommended dose is 80) and I’m really appreciating the results. Although the increase in energy and mind clarity isn’t huge at that small dose, it’s still enough of an improvement to make a difference in my life! With having CFS, my mitochondria really need that boost. Also, recently my kids all came down with a nasty flu bug, but I didn’t get sick, and I have to wonder if it was the MB, because I normally catch everything.
But I wanted to ask you, since MB is used as an antibiotic, previously for uti’s and more recently for Lyme, does that mean that it can harm levels of beneficial gut bacteria? Because if that’s the case, maybe it’s not good to take it on a regular basis…I was wondering about this as I seem to have developed some bathroom troubles recently and I was curious if there could be a connection. What do you think?
Jacqueline
Laura, I have listened to Mercola and others discuss MB, and I have never heard it mentioned that MB could affect gut flora. I did find this article on Lyme, and nothing in it is mentioned about the gut effect you mention. https://drtoddmaderis.com/methylene-blue-for-lyme-disease-and-bartonella
If you want to do some experimenting, cut the MB dosage to half (20 drops total per day) and see if your gut responds, and if not, then take a probiotic sometime between the morning and evening doses (Like Bio-Kult) and see what happens.
Look for a sweet spot. I would hate for you to lose that other relief you have gained. I’d love to know what you find out! Praying for you now!
Hugs, ~J
Laura in Ontario
Hello again! Just wanted to let you know that I emailed Dr. Gonzalez-Lima (the dr. in the video with Dr. Mercola) with my question about gut flora…he told me that Methylene Blue does NOT harm gut flora. I also asked him about taking MB with other supplements, iron in particular, and he told me to take MB blue with vitamin C first thing in the morning, and take my iron before bed, so they are well spaced out from each other. Just thought I would share what I learned! I am continuing to take MB daily but just at a very small dose. I found that on days when I took too much, I developed bladder irritation. So I’m keeping it down to around 20 drops per day and still noticing benefits.
Jacqueline
Laura in Ohio,
I love that you reached out to Dr. Gonzalez-Lima and he responded! I couldn’t imagine it causing gut problems, so this is good news.
Yes, I have learned to take my MB with Vitamin C in the morning and it has no chance of staining and goes down nicely.
Good to know about seperating MB from Iron and that it is so workable.
I appreciate your concern and finding out more for all of us!
God bless you,
Jacque
Doreen Spindler
Do you recommend the Compass Laboratory product in this article?
How can I find practitioners who would advise on specific applications for specific conditions?
Jacqueline
Hi, Doreen,
Yes, I ordered the product from Compass Labs, and it is what we are taking. Functional medical docs are my preference for several reasons. This explains it very wel: See “The Need for Real Healthcare…” right below the map
here: https://myfunctionalmedicinedoctor.org/
I would look for and work with a local functional medical doctor. Here is a place to start just for fun (these are the very pricey ones in the nation):
https://draxe.com/health/top-50-functional-integrative-medical-doctors/
What is a functional doctor? https://www.ifm.org/functional-medicine/what-is-functional-medicine/
Here are several directories to search your locale:
https://www.ifm.org/find-a-practitioner/
https://functionalmedicinedoctors.com/
I hope this helps!
Blessings,
Jacqueline
Kris
Jacque,
You mentioned that you used Zeolite for your Lyme after you had plateaued in your treatment, and that you added Methylene Blue later. Do you recommend that order? I have Lyme and have had good success with Cistus tea (recommended by my naturopath, according to Dr. Klinghardt’s recommendation.) But I have plateaued for the past year and a half, no further progress. I am wondering if I should begin with Zeolite for a while before starting the M Blue? Thank you for sharing all you learn with us.
Jacqueline
Hi, Kris,
Yes, I have found that detox first is important, and this is why.. When we got stuck, we learned the blockage was due to the fact that we were still quite toxic and what our ND was using could not get into the biofilms, brain and long bones, etc.. Once we got the toxins/hvy metals out of our deeper systems with TRS, our bodies were able to heal and actually USE the support supplements we took.
While our pathways were clogged, we were just applying bandaids. Many excellent foods and supplements like Cistus will work for a while, but because we are still loaded with toxins (causing inflammation and new autoimmune diseases to ramp up), they cease to be helpful.
I think you must have read our testimonial in this post: https://deeprootsathome.com/is-there-an-antidote-for-prion-protein-damage-from-the-spike-protein/
If you would like, email me at [email protected] and I can send you attachments that will give both insight and encouragement regarding Lyme, EBV, MS, dementia, Parkinson’s and more.
Sending peace,
Jacque
Bonnie White
Hi!
I was wondering if you thought there is any concern in ordering from Amazon instead of Compass Labs directly? I have heard others say other products were compromised when purchased from Amazon. I don’t know that they had proof, and it seems unlikely to me that those “in power” at Amazon would take the time and effort to tamper with holistic products at all of their warehouses, but I thought it was worth an ask.☺️. Thank you.
Jacqueline
Hi, Bonnie,
I do prefer to purchase right from the company. And I doubt Amazon can alter the products.
It would take a whole repackaging system and lots of manpower unless they had a robot warehouse to so it… they are laying off right now.
Hope that helps!
Jacque
Carol
Can you tell me how long you would need to Take Methylene Blue for recurrent urinary tract in elderly person?
Jacqueline
Hi, Carol,
I would think it would be just a few days (2-3) to see a noticeable difference. It will clean the whole urinary tract.
The patient would see her urine be slightly blue-green and that indicates that it is reaching the bladder in sufficient quantity.
I personally would use 6-8 drops MB (2-3 times a day for 2-3 days) in an inch or 2 of water and then add vitamin C – enough to denature the color to a pale blue after several minutes of occasional stirring.. Drink it down and rinse down with clear water.
My teeth have never stained this way.
Praying for your friend now!
Sending peace,
Jacqueline
honingbij
Dear Jacqueline:
Do you think MB might be helpful with the withdrawal symptoms of tapering off amitriptyline?
I was prescribed it years ago for migraine prophylaxis. I’m currently at 4.12 mg [from 75 mg], so I’m seeing the light at the end of the tunnel, but there’s still a long way to go.
Jacqueline
Hi, Honingbij,
If you would email me (just copy and paste your helpful details), there are several things you can do to get of this drug (slowly like you are doing, but with less difficulty and a healthier outcome).
I’m at [email protected]
Sending peace,
Jacque
honingbij
Thank you from the bottom of my heart, Jacque!
I’ve sent you an email.